Root® with Next Generation SedLine Brain Function Monitoring, available for adult and paediatric patients (one year old and above), helps clinicians monitor the state of the brain under anaesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals.
Next Generation SedLine Features:
Next Generation SedLine features an enhanced signal processing engine which provides an enhanced Patient Sate Index (PSi), a processed EEG parameter related to the effect of anaesthetic agents.
To evaluate the performance of Original PSi and Next Generation PSi, independent EEG experts reviewed cases with both Original PSi and Next Generation PSi (blinded to the version), along with additional clinical information (MOAAS scores, EEG waveforms, drug doses, and vital signs). Compared to the expert-assessed anaesthetic depth, an error was defined as a case when expert assessment of PSi was ‘Low’ or ‘High’ and success was defined as a case when the expert assessment of PSi was ‘Good’.
EMG is a common confounding factor that can interfere with EEG signals used in brain function monitoring.2 Researchers have found that EMG interference existed in up to 38% of monitored patients.3 Next Generation SedLine utilises Masimo’s Parallel Signal Processing Engines to extract a clearer EEG signal and compute a processed EEG parameter (PSi) less influenced by EMG.
This image captures a moment when Next Generation SedLine detects EMG in the two engines depicted.
Power across all frequency bands decreases with age.4 Low power can present a challenge for conventional brain function monitors.2
The subjects above were administered Propofol and were in a comparable anaesthetic state.5
When computing PSi, Next Generation SedLine uses adaptive signal processing with band-independent features to search for EEG features across many frequency bands and offer improved PSi performance in cases of low power EEG.
Next Generation SedLine offers clinicians the flexibility of choosing to display either an enhanced Multitaper Density Spectral Array (DSA) or a standard Hanning DSA. The DSA contains left and right spectrograms representing the power of the EEG on both sides of the brain.
When using a Multitaper DSA, EEG data are transformed into the frequency domain, which may provide a better display of EEG features.
The Next Generation SedLine module easily plugs into the Root patient monitoring platform via Masimo Open Connect® (MOC-9®) ports. Root’s customisable, easily-interpretable display offers multiple views of brain monitoring information, expanding visibility in the operating theater and intensive care unit.
Next Generation SedLine can be used simultaneously with O3® Regional Oximetry on the Root platform for a more complete picture of the brain.
Explore the Root Platform and Brain Monitoring Sensors & Cables
Retrospective analysis of clinical data on file.
Purdon P et al. Brit J of Anaesth. 10.1093 46-57.
Narasway et al. Critical Care Med. 2002 Jul;30(7):1483-7.
Lobo, Francisco A., and Stefan Schraag. Limitations of anaesthesia depth monitoring. Current Opinion in Anesthesiology. 24, no. 6 (2011): 657-664.
Masimo Data on File.
The SedLine System with paediatric indication is not licensed for sale in Canada.
For professional use. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.
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