Clinical Evidence

Clinical Evidence


Clinical Studies

Masimo is passionate about making innovative technologies that give clinicians the tools they need to do what is best for patient care. That's why it is gratifying to see so many clinicians and clinical researchers take the time to evaluate our products and technologies.

Click on the links below to read featured studies for Masimo’s technologies, or in the sections below for access by subject area to all studies.

Featured Clinical Studies


Masimo SET® Pulse Oximetry


Harris BU, Char DS, Feinstein JA, Verma A, Shiboski SC, Ramamoorthy C. Pediatr Crit Care Med. 2016 Apr;17(4):315-20.

Shah N., Ragaswamy H.B., Govindugari K., Estanol L. J Clin Anesth. 2012 Aug;24(5):385-91.

Castillo A., Deulofeut R., Critz A., Sola A. Acta Paediatr. 2011 Feb;100(2):188-92.

de-Wahl Granelli A., Wennergren M., Sandberg K., Mellander M., Bejlum C., Inganäs L., Eriksson M., Segerdahl N., Agren A., Ekman-Joelsson B.M., Sunnegårdh J., Verdicchio M., Östman-Smith I. BMJ. 2009;Jan 8;338.

Durbin C.G. Jr., Rostow S.K. Crit Care Med. 2002 Aug;30(8):1735-40.

Hay W.W., Rodden D.J., Collins S.M., Melara D.L., Hale K.A., Fashaw L.M. J Perinatol. 2002 Jul-Aug;22(5):360-6.

Barker S.J. Anesth Analg. 2002 Oct;95(4):967-72.

Thiele RH, Rea KM, Turrentine FE, Friel CM, Hassinger TE, Goudreau BJ, Umapathi BA, Kron IL, Sawyer RG, Hedrick TL. Journal of the American College of Surgeons (2015), doi: 10.1016/j.jamcollsurg.2014.12.042.

Forget P, Lois F, de Kock M. Anesth Analg. 2010 Oct;111(4):910-4.

Cannesson M., Desebbe O., Rosamel P., Delannoy B., Robin J., Bastien O., Lehot J.J. Br J Anaesth. 2008 Aug;101(2):200-6.

Taenzer A.H., Pyke J.B., McGrath S.P., Blike G.T. Anesthesiology. 2010 Feb;112(2):282-7.

Taenzer A.H., Blike, G. T. APSF Newsletter 2012. Available at: Accessed June 14, 2012.

Awada WN, Mohmoued MF, Radwan TM, Hussien GZ, Elkady HW. J Clin Monit Comput. 2015 Feb 4. [Epub ahead of print] PubMed PMID: 25649717.

Ehrenfeld JM, Henneman JP, Bulka CM, Sandberg WS. 2014. J Blood Disorders Transf 5:237.doi:10.4172/2155-9864.1000237.

Patino M, Schultz L, Hossain M, Moeller J, Mahmoud M, Gunter J, Kurth CD. Anesth Analg. 2014 Jul 17. [Epub ahead of print] PubMed PMID: 25036374.

Frasca D., Dahyot-Fizelier C., Catherine K., Levrat Q., Debaene B., Mimoz O. Crit Care Med. 2011 Oct;39(10):2277-82.

Macknet M.R., Allard M., Applegate R.L., Rook J. Anesth Analg. 2010 Dec;111(6):1424–6.

Awada WNFM et al. Anesth Analg 2013; (117 suppl): 50 (abstract).

Mimoz O., Benard T., Gaucher A., Frasca D., Debaene B. Br J Anaesth. 2012 May;108(5):872-5.

Ramsay M.A., Lagow E., Usman M. 65th Annual Post Graduate Assembly in Anesthesiology. December 9-11, 2011. Abs P-9137.

Goudra B.G., Penugonda L. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A246.

Macknet M.R., Kimball-Jones P.L., Applegate R.L., Martin R.D., Allard M.W. Anesthesiology. 2007; 107: A84.

Roth D., Herkner H., Schreiber W., Hubmann N., Gamper G., Laggner A.N., Havel C. Ann Emerg Med. 2011 Jul;58(1):74-9.

Hampson N.B. Am J Emerg Med. 2012 Nov;30(9):2021-4.

Annabi E.H., Barker S,J. Anesth Analg. 2009;108:898–9.

Tsymbal E, Ayala S, Singh A, Applegate RL 2nd, Fleming NW. [published online ahead of print, 2020 May 18]. J Clin Monit Comput. 2020;10. doi:10.1007/s10877-020-00531-w

Alday E, Nieves JM, Planas A. J Cardiothorac VascAnesth. 2020 Feb;34(2):417-422.

Scheeren TWL, FJ Belda, A Perel. J Clin Monit Comput, 2017. DOI 10.1007/s10877-017-0049-4.

Applegate RL 2nd, Dorotta IL, Wells B, Juma D, Applegate PM. Anesth Analg. 2016 Mar 22. [Epub ahead of print] PubMed PMID: 27007078.

Szmuk P, Steiner JW, Olomu, PN, Ploski, RP, Sessler, DI, Ezri, T. Anesthesiology 2016; 124:00-00. doi:10.1097/ALN.0000000000001009

Szmuk P, Steiner J., Olomu P., Dela Cruz J., Sessler D. American Society of Anesthesiologists 2014; BOC12.

Redford D, Paidy S, Kashif F. Anesth Analg. 2014 Dec; 119(6):1315-1319. PubMed PMID: 25405692.

Drover D.R., Lemmens H.J., Pierce E.T., Plourde G., Loyd G., Ornstein E., Prichep L.S., Chabot R.J., Gugino L. Anesthesiology 2002; 97:82–9.

Hildebrandt T., Espelund M., Olsen K.S. Anaesthesia. 2010 Oct;65(10):1017-21.

Bräunlich et al. Int J Chron Obstruct Pulmon Dis 2019;(14):1411-1421.

Biselli et al. Eur Respir J 2018;51:1702251.

Biselli et al. J Appl Physiol (1985). 2017;122(1):82-88.

Bräunlich J et al.
Int J Chron Obstruct Pulmon Dis. 2016;(11):1077-1085.

Tengberg LT, Bay-Nielsen M, Bisgaard T, Cihoric M, Lauritsen MI, Foss NB. Br J Surg. 2017 Mar;104(4):463-471.

Sadique Z, Harrison DA, Grieve R, Rowan KM, Pearse RM; OPTIMISE study group. Perioper Med (Lond). 2015;4:13. Published 2015 Dec 14.

Huddart S, Peden CJ, Swart M, et al. Br J Surg. 2015;102(1):57-66.

Pearse et al. JAMA. 2014;311(21):2181-2190.

Hata J, Stotts C, Shelsky C, Bayman E, Frazier A, Wang J, Nickel E. J Crit Care. 2011;26(2):224.E1-8.

The use of the trademark Patient SafetyNet is under license from University HealthSystem Consortium.

Masimo devices with SpHb, SpCO, and/or SpMet monitoring are not intended to replace laboratory blood testing. Blood samples should be analysed by laboratory instruments prior to clinical decision making.

Duplicate abstracts or publications are excluded

This section is intended to provide access to clinical studies conducted using Masimo noninvasive technologies, parameters, and products. We cannot guarantee that all published clinical studies, abstracts and research are listed here. To view individual clinical studies please click on the appropriate tab.

Some uses of the manufacturer’s devices described in the information may not have been approved or cleared by the FDA. See manufacturer labeling for the indications in the product’s cleared indications for use statement.

Clinical evidence is provided to illustrate the performance and accuracy of Masimo technologies. Federal law restricts Masimo devices for medical uses to sale by or on the order of a physician.